Effects of iTBS on Motor Recovery of Lower Extremity in Chronic Stroke Patients.
Launched by DANDERYD HOSPITAL · Jul 9, 2025
Trial Information
Current as of July 24, 2025
Not yet recruiting
Keywords
ClinConnect Summary
This clinical trial is studying a new way to help people recover movement in their legs after having a stroke. It uses a special, non-invasive brain stimulation technique called intermittent Theta Burst Stimulation (iTBS) to see if it can improve walking and leg strength for people who have had a stroke more than six months ago. The study also looks at how this treatment may change brain activity and connections to better understand how recovery happens.
People who might join this study are adults over 18 who have had a stroke at least six months ago and still have some weakness in their legs but can walk with some support. The trial is open to both men and women. Participants will receive brain stimulation as part of their rehabilitation, and the researchers will carefully check how their brain and leg function change over time. Some people won’t be able to join, like those with metal implants, epilepsy, severe memory problems, or other health issues that make physical training difficult. This study is not yet recruiting participants but aims to offer new hope for improving leg movement after stroke.
Gender
ALL
Eligibility criteria
- Inclusion Criteria:
- • Age over 18
- • Chronic stroke (\>6 months)
- • Residual hemiparesis FAC ≥3
- Exclusion Criteria:
- • Metal implants
- • Epilepsy/seizures
- • Pregnancy
- • Claustrophobia (related to MRIs exams)
- • Severe cognitive impairment
- • Untreated or unstable depression/anxiety
- • Other disabilities prohibiting intensive physical training
About Danderyd Hospital
Danderyd Hospital is a leading medical institution in Sweden, renowned for its commitment to advancing healthcare through innovative clinical research and trials. As a prominent sponsor of clinical studies, the hospital leverages its extensive expertise and state-of-the-art facilities to facilitate groundbreaking research across various medical disciplines. Danderyd Hospital collaborates with academic institutions, industry partners, and healthcare professionals to enhance patient care and contribute to the development of new therapies and treatments. With a focus on ethical standards and patient safety, Danderyd Hospital aims to improve health outcomes and drive medical advancements that benefit the wider community.
Contacts
Jennifer Cobb
Immunology at National Institute of Allergy and Infectious Diseases (NIAID)
Locations
Stockholm, , Sweden
Patients applied
Trial Officials
Susanne Palmcrantz, PhD, Associate Professor
Principal Investigator
Dep of Clinical Sciences, Karolinska Institutet
Timeline
First submit
Trial launched
Trial updated
Estimated completion
Not reported