Effects of iTBS on Motor Recovery of Lower Extremity in Chronic Stroke Patients.

Launched by DANDERYD HOSPITAL · Jul 9, 2025

Keywords

ClinConnect Summary

This clinical trial is studying a new way to help people recover movement in their legs after having a stroke. It uses a special, non-invasive brain stimulation technique called intermittent Theta Burst Stimulation (iTBS) to see if it can improve walking and leg strength for people who have had a stroke more than six months ago. The study also looks at how this treatment may change brain activity and connections to better understand how recovery happens.

People who might join this study are adults over 18 who have had a stroke at least six months ago and still have some weakness in their legs but can walk with some support. The trial is open to both men and women. Participants will receive brain stimulation as part of their rehabilitation, and the researchers will carefully check how their brain and leg function change over time. Some people won’t be able to join, like those with metal implants, epilepsy, severe memory problems, or other health issues that make physical training difficult. This study is not yet recruiting participants but aims to offer new hope for improving leg movement after stroke.

Gender

ALL

Eligibility criteria

• Inclusion Criteria:
• • Age over 18
• • Chronic stroke (\>6 months)
• • Residual hemiparesis FAC ≥3
• Exclusion Criteria:
• • Metal implants
• • Epilepsy/seizures
• • Pregnancy
• • Claustrophobia (related to MRIs exams)
• • Severe cognitive impairment
• • Untreated or unstable depression/anxiety
• • Other disabilities prohibiting intensive physical training