Effects of iTBS on Motor Recovery of Upper Extremity in Chronic Stroke Patients.

Launched by DANDERYD HOSPITAL · Jul 9, 2025

Keywords

ClinConnect Summary

This clinical trial is studying a new way to help people recover movement and function in their arms and hands after having a stroke, especially those who have lived with stroke-related weakness for more than six months. The researchers are testing a treatment called intermittent Theta Burst Stimulation (iTBS), which is a safe, non-invasive method that uses gentle brain stimulation to support rehabilitation and improve motor recovery. They also want to understand how this treatment might change brain activity and connections.

People who are eligible to join this study are adults over 18 years old who have had a stroke at least six months ago and still have some weakness in their arm or hand. However, the study is not yet open for enrolling participants. If you take part, you can expect to receive this brain stimulation as part of your therapy, and you will likely have brain scans to help the researchers observe changes. Some people won’t be able to join, such as those with metal implants, epilepsy, severe mental health conditions, pregnancy, or other health issues that make intense physical therapy difficult. This study aims to find new ways to improve arm and hand function after stroke, offering hope for better recovery in the long term.

Gender

ALL

Eligibility criteria

• Inclusion Criteria:
• • Age over 18
• • Chronic stroke (\>6 months)
• • Residual hemiparesis FM-UE\>17
• Exclusion Criteria:
• • Metal implants
• • Epilepsy/seizures
• • Pregnancy
• • Claustrophobia (related to MRIs exams)
• • Severe cognitive impairment
• • Untreated or unstable depression/anxiety
• • Other disabilities prohibiting intensive physical training