Effect of Ultra-Low Tidal Volume on Mechanical Power During Heart Bypass Surgery

Launched by KONYA CITY HOSPITAL · Jul 16, 2025

Keywords

ClinConnect Summary

This clinical trial is studying a new way to help protect the lungs during heart bypass surgery, which is done to treat coronary artery disease (blocked blood flow to the heart). During this surgery, a machine takes over the work of the heart and lungs. The trial is testing whether using very gentle, low-volume breaths (called ultra-low tidal volume ventilation) during this time can reduce the strain on the lungs and lead to better breathing after surgery. The researchers want to see if this method helps patients breathe easier, get off the breathing machine faster, and spend less time in the intensive care unit (ICU) compared to the usual approach where patients do not receive these small breaths during the procedure.

Adults over 18 years old who are having planned heart bypass surgery and are generally in fair health (classified as ASA II to IV) may be eligible to participate, unless they have serious lung problems, uncontrolled asthma, severe heart failure, or other specific health issues. Participants will be randomly assigned to receive either the ultra-low volume breaths or no breaths during part of their surgery. Throughout the process, doctors will carefully monitor lung function, breathing power, and recovery times. The goal is to find safer ways to protect the lungs during surgery and help patients recover more quickly.

Gender

ALL

Eligibility criteria

• Inclusion Criteria:
• • Patients of either sex aged over 18 years
• • Patients classified as ASA II-IV
• • Patients scheduled for elective CABG
• Exclusion Criteria:
• • Presence of severe COPD
• • Uncontrolled bronchial asthma
• • Decompensated heart failure (NYHA class III-IV)
• • Pulmonary hypertension
• • History of lung surgery
• • Morbid obesity (BMI \>35)
• • Emergency surgery cases
• • Patients who decline to participate in the study