A Digital Treatment Platform for the Delivery of Home-Based Sequential Therapy in Patients With Glioma

Launched by MAYO CLINIC · Jul 17, 2025

Keywords

ClinConnect Summary

This clinical trial is looking at how well a digital treatment platform, delivered through a mobile app, can help patients with glioma—a type of brain tumor—receive therapy at home. Because specialized brain cancer care is hard to access for many people due to distance, disability, or cost, this app aims to connect patients with their care team continuously without needing to travel. The goal is to make treatment easier to follow and to help more patients take part in clinical trials, which could speed up the discovery of new treatments.

Adults aged 18 and older with glioma who are starting or continuing treatment for at least six months may be eligible. Patients should be well enough to participate, with a good level of daily functioning, and are expected to live at least six more months. Participants will use the app to receive their therapy and stay in touch with their doctors from home, while also attending scheduled check-ins and assessments. This study is not yet recruiting, but it offers a promising way to improve care and support for people living with glioma.

Gender

ALL

Eligibility criteria

• Inclusion Criteria:
• • Age ≥ 18 years
• • Diagnosis of glioma and intention to treat with either new or ongoing systemic therapy for at least 6 months.
• • NOTE: Patient may be enrolled following completion of surgery and/or radiation therapy for newly diagnosed or recurrent tumor.
• • NOTE: Any number of prior recurrences is permitted
• • Eastern Cooperative Oncology Group (ECOG) performance status of 0, 1, or 2, AND Karnofsky performance status (KPS) of ≥ 60
• • Expected survival ≥ 6 months in the opinion of treatment team
• • Willing and able to adhere with the protocol for the duration of the study including undergoing treatment, and attending scheduled visits, and examinations
• • Negative pregnancy test ≤ 8 days prior to registration for persons of childbearing potential only
• • Provide written informed consent
• • Ability to complete assessments and questionnaires by themselves or with assistance
• Exclusion Criteria:
• • Pregnant or nursing, imprisoned, or lacking capacity for understanding
• • Uncontrolled and/or intercurrent illness or other condition which limits safety of or compliance with study proceedings