Cervical and Endometrial Cancer Screening in Patients Seeking Gender-Affirming Hysterectomy

Launched by UNIVERSITY OF MINNESOTA · Jul 10, 2025

Keywords

ClinConnect Summary

This clinical trial is studying how often people who are transgender or gender diverse get tested for cervical and uterine (endometrial) cancer before having a gender-affirming hysterectomy, which is surgery to remove the uterus. The goal is to understand whether these cancer screenings are needed, how often they are done, and how patients feel about these tests. The study also looks at the results from the surgery to see if the screenings matched what was found during the procedure. This information will help doctors create better guidelines for cancer screening in transgender and gender-diverse patients in the future.

People who are 18 years or older, identify as transgender or gender diverse, and have either had or are planning to have a hysterectomy can take part in this study. Participants need to be able to read, write, and understand English and give their consent to join. If you join the study, you may be asked about your past cancer screenings and your experience with them. This study is currently recruiting participants who meet these criteria and want to help improve care for transgender and gender-diverse individuals.

Gender

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Eligibility criteria

• Inclusion Criteria:
• • 18 years and older
• • Able to provide voluntary written consent prior to the performance of any research related activity. Patients who can provide informed consent
• • Able to understand, speak, read, and write in English
• • Patients who have undergone hysterectomy, or plan to have a hysterectomy
• • Patients who are transgender and gender diverse"
• Exclusion Criteria:
• • Opted out of research
• • \<18 years old
• • Lacks capacity to consent/has diminished capacity to consent
• • Cannot provide informed consent
• • Those on the study's community advisory board