Neutrophil to Lymphocyte Ratio and Postdural Headache

Launched by ISTINYE UNIVERSITY · Jul 10, 2025

Keywords

ClinConnect Summary

This clinical trial is studying whether a simple blood test done before a cesarean section can help predict if a woman will develop a headache called post-dural puncture headache (PDPH). This type of headache can happen after spinal anesthesia, which is commonly used during cesarean deliveries. Researchers are especially interested in a specific blood marker called the neutrophil-to-lymphocyte ratio (NLR), which reflects the body’s inflammation levels.

Women who are 18 years or older, having a cesarean section with spinal anesthesia, and who have had routine blood tests before surgery may be eligible to join. Participants will not have any blood disorders or infections and must have complete medical records for follow-up. If you join, your medical records and blood test results will be reviewed to see if there is a connection between your blood markers and the chance of getting this type of headache after surgery. This study is still recruiting patients, and it aims to help doctors better predict and manage headaches after spinal anesthesia in the future.

Gender

FEMALE

Eligibility criteria

• Inclusion Criteria:
• • Women aged 18 years or older
• • Underwent elective or emergency cesarean section under spinal anesthesia
• • Had complete preoperative complete blood count (CBC) data available
• • No known hematological or inflammatory disease
• • No intraoperative complications recorded
• • Medical records accessible for postoperative follow-up regarding PDPH symptoms
• Exclusion Criteria:
• • Age under 18
• • Absence of preoperative complete blood count data
• • Presence of hematologic malignancy, active infection, autoimmune disease, or immunosuppressive therapy
• • Platelet count \<150,000/mm³ or INR \>1.5
• • Incomplete or missing medical records