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Search / Trial NCT07076043

Multi-product PrEP Delivery to Young Women Seeking Reproductive Health Services and Coverage of HIV Prevention

Launched by UNIVERSITY OF ALABAMA AT BIRMINGHAM · Jul 17, 2025

Trial Information

Current as of August 19, 2025

Recruiting

Keywords

Hiv Prevention Pr Ep Adolescent Girls And Young Women Kenya Stepped Wedge Cluster Randomized Trial

ClinConnect Summary

This clinical trial is studying new ways to help young women prevent HIV, a virus that affects the immune system. Researchers are introducing a new HIV prevention product called the dapivirine ring—a small, flexible ring that women can wear inside the vagina to lower the chance of getting HIV. The study will take place at 12 health clinics in Kenya that already offer daily oral PrEP (a pill that helps prevent HIV). The goal is to see if offering more than one option for HIV prevention, like the ring along with the pill, helps more young women start and continue using these methods.

Young women between 18 and 30 years old who are visiting these clinics for reproductive health services—such as family planning, pregnancy care, or postnatal care—may be eligible to join the study. Participants will receive counseling about their HIV prevention choices and can decide whether to use the dapivirine ring, oral PrEP, or both. The study team will support the clinics in providing these options and will follow how many women choose and stick with these prevention methods over time. This trial is currently recruiting participants, and anyone interested should be able to read or speak Kiswahili or English and be willing to give informed consent to take part.

Gender

FEMALE

Eligibility criteria

  • Inclusion Criteria for Adolescent Girls and Young Women seeking reproductive health services:
  • Age ≥18 years and ≤30years. Seeking a reproductive health service from one of the project facilities (reproductive health services include but are not limited to family planning, maternal and child health, postnatal care).
  • AGYW receiving reproductive health-related services through OPD, or other departments are eligible. AGYW receiving reproductive health-related services through other departments are eligible.
  • Willing and able to partake in an informed consent process. Able to speak and read in Kiswahili or English.

About University Of Alabama At Birmingham

The University of Alabama at Birmingham (UAB) is a prominent academic institution and research hub dedicated to advancing healthcare through innovative clinical trials. Renowned for its commitment to medical discovery and education, UAB conducts cutting-edge research across a wide array of disciplines, including oncology, cardiology, neurology, and public health. With a robust infrastructure for clinical research, UAB fosters collaboration among interdisciplinary teams, leveraging state-of-the-art facilities and resources to enhance the translation of scientific findings into effective treatments and interventions. As a leader in clinical research, UAB aims to improve patient outcomes and contribute to the broader medical community through rigorous trial design and implementation.

Locations

Thika, Kiambu, Kenya

Patients applied

0 patients applied

Trial Officials

Nelly Mugo, MBChB, MMed, MPH

Principal Investigator

Kenya Medical Research Institute

Timeline

First submit

Trial launched

Trial updated

Estimated completion

Not reported