Comparison of Adenoma Detection Rate in 3D vs. 2D Surveillance Colonoscopy

Launched by NATIONAL TAIWAN UNIVERSITY HOSPITAL · Jul 19, 2025

Keywords

ClinConnect Summary

This clinical trial is studying whether using a 3D colonoscopy can help doctors find more colon polyps and adenomas (which are small growths that can sometimes turn into cancer) compared to the standard 2D colonoscopy. Finding and removing these growths during a colonoscopy is very important because it helps prevent colorectal cancer. The study especially looks at how well 3D colonoscopy detects flat or hard-to-see growths, which are often missed with regular colonoscopy and can increase the risk of cancer later on.

The trial is for adults aged 40 and older who have had a colonoscopy with polyp removal at least one year ago and now need a follow-up colonoscopy to check for new growths. People with certain conditions, like hereditary polyposis, inflammatory bowel disease, or those who have had part of their colon removed, won’t be eligible. Participants will have a surveillance colonoscopy using either the 3D or 2D method, and the study will compare which method finds more adenomas. This research could help improve how often and when people need future colonoscopies, making colon cancer prevention even better.

Gender

ALL

Eligibility criteria

• Inclusion Criteria:
• • Subjects who are 40 years of older
• • Subjects who receive colonoscopy and polypectomy more the 1 year
• • Subjects who need surveillance colonoscopy
• Exclusion Criteria:
• • Contraindication for colonoscopy
• • Subjects with familiar or hereditary polyposis
• • Subjects with history of colectomy
• • Inadequate bowel cleansing level
• • Subjects with inflammatory bowel disease