Adhesion Prevention in ASBO Surgery Using 4DryField® PH

Launched by ALESSIO GIORDANO · Jul 14, 2025

Keywords

ClinConnect Summary

This clinical trial is studying whether a special product called 4DryField® PH can help prevent a common problem after abdominal surgery called adhesive small bowel obstruction (ASBO). ASBO happens when bands of scar tissue, called adhesions, form inside the belly after surgery and block the intestines, causing pain and other complications. Although surgery can fix this blockage, it often leads to new adhesions, and the problem can come back. 4DryField® PH is a starch-based gel that surgeons apply during surgery to create a temporary barrier, which may help the body heal without forming as many adhesions. This study will look at whether using 4DryField® PH during surgery lowers the chance of ASBO coming back within a year and how it affects recovery compared to not using the product.

Adults aged 18 and older who are having surgery to treat ASBO may be eligible to join the study, provided they can give consent and agree to follow-up visits. People with certain conditions like widespread infection in the abdomen (peritonitis), active cancer inside the belly, or who are pregnant or breastfeeding cannot participate. If you join, you can expect to have the 4DryField® PH applied during your surgery and then be monitored for up to 12 months to see how you recover and if the blockage returns. This trial is not yet recruiting, but it aims to find better ways to reduce complications and improve outcomes after surgery for bowel obstruction caused by adhesions.

Gender

ALL

Eligibility criteria

• Inclusion Criteria:
• • Age ≥ 18 years
• • Undergoing surgical treatment for adhesive small bowel obstruction (ASBO)
• • Ability and willingness to provide informed consent
• • Willingness to adhere to follow-up visits
• Exclusion Criteria:
• • Presence of peritonitis
• • Intra-abdominal active malignancy
• • Pregnancy or breastfeeding