Comparison of Lidocaine, Mepivacaine, and Dry Needling in Myofascial Pain Syndrome

Launched by SÜMER MÜNEVVEROĞLU · Jul 14, 2025

Keywords

ClinConnect Summary

This clinical trial is studying ways to treat pain in the muscles used for chewing, which is often linked to a condition called myofascial pain syndrome. The study compares three treatments: dry needling (a technique where thin needles are inserted into painful muscle spots), and injections with either lidocaine or mepivacaine, which are medicines that help numb pain. The goal is to find out which treatment works best to reduce muscle pain, improve jaw function, and help with related symptoms like mood changes.

Adults between 18 and 64 years old who have active painful spots on both sides of their chewing muscles may be able to join. Participants will receive one treatment each week for three weeks. Before and after the treatments, their pain levels, mood, and jaw problems will be checked using simple questionnaires and pain rating scales. People who have had recent treatments for jaw disorders, certain medical conditions, or who are pregnant won’t be able to join. This study can help improve care for people with muscle-related jaw pain by finding the most effective treatment option.

Gender

ALL

Eligibility criteria

• Inclusion Criteria:
• • Adults aged 18 to 64 years
• • Presence of bilateral active myofascial trigger points in both the masseter and temporalis muscles
• • Pain provoked by approximately 1 kg of external digital pressure on trigger points
• • Willingness to participate and provide informed consent
• Exclusion Criteria:
• • Previous or ongoing treatment for temporomandibular disorders (e.g., occlusal splints, botulinum toxin injections)
• • Presence of systemic neuromuscular disease
• • Pregnancy or breastfeeding
• • Use of analgesics, muscle relaxants, or antidepressants within the past 2 weeks
• • Active infection, tumor, or trauma in the orofacial region