Assessment of Hard and Soft Tissue Changes Following XCM Versus FGG Simultaneous With Dental Implant Placement

Launched by CAIRO UNIVERSITY · Jul 22, 2025

Keywords

ClinConnect Summary

This clinical trial is studying two different methods to help improve the gums and bone around dental implants for people who have lost teeth. When a tooth is lost, the area where it used to be can shrink and lose important gum tissue, which can make it harder for implants to stay healthy over time. The study is comparing two techniques—using a special soft tissue graft called XCM versus a traditional gum graft called FGG—both done at the same time as placing the dental implant. The goal is to find out which method better supports the gums and bone, helping implants last longer and stay healthy.

Adults over 18 who have a narrow band of firm gum tissue (2 millimeters or less) around the missing tooth area and enough bone to place an implant may be eligible to join. Participants need to have good oral hygiene and be willing to follow treatment instructions. People with active gum disease, infections, certain medical conditions, heavy smoking habits, or other health issues may not qualify. If you take part, you can expect to have the gum tissue around your implant treated using one of the two methods, and your healing and tissue changes will be carefully monitored. This study aims to help improve care for people needing implants by finding the best way to support healthy gums and bone.

Gender

ALL

Eligibility criteria

• Inclusion Criteria:
• • 1. Adults above the age of 18 years.
• • 2. Presence of 2mm or less of keratinized tissue width
• • 3. Sufficient alveolar ridge width minimum of 6 mm
• • 4. Patients with good oral hygiene as evidenced by plaque index (PI)\<1 and showing cooperation or compliance with treatment.
• Exclusion Criteria:
• • 1. Patients diagnosed with periodontal diseases (Caton et al., 2018).
• • 2. Acute active infection at implant sites
• • 3. Patients with medical conditions that would compromise the surgical procedures; uncontrolled diabetes mellitus, taking intravenous bisphosphonates for treatment of osteoporosis and radiotherapy
• • 4. Patients with parafunctional habits.
• • 5. Smokers (≥10 cigarettes per day),