Dual Subsartorial Versus Adductor Canal Block Versus Femoral Nerve Block for Postoperative Analgesia in Patients Undergoing Total Knee Arthroplasty

Launched by TANTA UNIVERSITY · Jul 16, 2025

Keywords

ClinConnect Summary

This clinical trial is studying different ways to manage pain after knee replacement surgery, which is called total knee arthroplasty. Specifically, it compares three types of nerve blocks—methods where medicine is injected near nerves to reduce pain: the dual subsartorial block, the adductor canal block, and the femoral nerve block. The goal is to find out which method works best to control pain after surgery.

Adults aged 18 to 75 who are having knee replacement surgery under general anesthesia may be eligible to participate, as long as they are generally healthy (meeting certain health status guidelines) and do not have serious conditions like severe knee deformities, kidney problems, nerve issues, infections at the injection site, blood clotting problems, allergies to the anesthetic medicine, or long-term opioid use. Participants will receive one of the three nerve blocks during surgery and will be monitored for how well their pain is controlled afterward. This study has not started recruiting yet, but it aims to help improve pain relief options for people undergoing knee replacement in the future.

Gender

ALL

Eligibility criteria

• Inclusion Criteria:
• • Age from 18 to 75 years.
• • Both sexes.
• • American Society of Anesthesiology (ASA) physical status I-II.
• • Undergoing total knee arthroplasty (TKA) under general anesthesia.
• Exclusion Criteria:
• • Severe valgus deformity.
• • Acute/chronic kidney disease.
• • Neurological deficit.
• • Cognitive dysfunction.
• • Local infection at the site of injection.
• • Coagulopathy.
• • Hypersensitivity and/or allergies to local anesthetic (LA) or any of the study medications.
• • Chronic opioid consumption (daily or almost daily use of opioids for \> three months).
• • Operative limb neuropathy.