External Oblique and Rectus Abdominis Plane Block Versus Quadratus Lumborum Block for Postoperative Analgesia in Patients Undergoing Laparoscopic Cholecystectomy

Launched by TANTA UNIVERSITY · Jul 16, 2025

Keywords

ClinConnect Summary

This clinical trial is studying two different types of nerve blocks—called the external oblique and rectus abdominis plane (EXORA) block and the quadratus lumborum block (QLB)—to see which one works better to reduce pain after gallbladder surgery done with small cuts (laparoscopic cholecystectomy). Both blocks involve injecting medicine near specific muscles to numb the area and help control pain after surgery.

The study is open to adults aged 18 to 65 who are healthy enough for surgery (based on certain health criteria) and are scheduled to have this type of gallbladder surgery under general anesthesia. People with allergies to numbing medicines, ongoing opioid use, certain medical conditions like high blood pressure or uncontrolled diabetes, or infections near the injection site cannot join. If you participate, you will receive one of the two nerve blocks during your surgery, and the doctors will monitor your pain levels afterward to see which block provides better relief. This information could help improve pain management for patients having this common surgery in the future.

Gender

ALL

Eligibility criteria

• Inclusion Criteria:
• • Age from 18 to 65 years.
• • Both sexes.
• • American Society of Anesthesiology (ASA) physical status I-II.
• • Undergoing laparoscopic cholecystectomy (LC) under general anesthesia.
• Exclusion Criteria:
• • History of allergies to local anesthetics.
• • Opioid dependency.
• • Bleeding or coagulation disorders.
• • Psychiatric and neurological disorder.
• • Local infection at the site of injection.
• • Body mass index (BMI) \> 35.
• • Hypertension.
• • Uncontrolled diabetes mellitus.