Temporal Change in Parasternal Thickening Fraction as a Predictor for Weaning

Launched by CAIRO UNIVERSITY · Jul 16, 2025

Keywords

ClinConnect Summary

This clinical trial is studying a new way to help doctors decide the best time to take patients off mechanical ventilation—a machine that helps people breathe when they can’t do so on their own. The study looks at how changes in a specific muscle near the chest (measured using ultrasound) might predict if a patient is ready to breathe independently without the machine. Finding the right time to stop mechanical ventilation is very important because removing it too early or too late can cause serious problems.

People who might join this study are adults who have been on a breathing machine for at least 24 hours and are considered ready to start the process of weaning off it. However, people who have had a tracheostomy (a breathing tube inserted into the neck), have certain muscle diseases, or if ultrasound images can’t be taken properly won’t be able to participate. If you join, you can expect to have ultrasound exams to check the chest muscle over time as doctors decide when to remove the breathing machine. This study is not yet recruiting participants but aims to improve safety and outcomes for patients who need help breathing.

Gender

ALL

Eligibility criteria

• Inclusion Criteria:
• • - Mechanically ventilated for 24 hours or more ready for weaning
• Exclusion Criteria:
• • Refusal Tracheostomized Inability to obtain ultrasound views patients with neuromuscular disease