Effects of Low-Flow Sevoflurane Anesthesia on Pulmonary Function During One-Lung Ventilation

Launched by DR ABDURRAHMAN YURTASLAN ANKARA ONCOLOGY TRAINING AND RESEARCH HOSPITAL · Jul 24, 2025

Keywords

ClinConnect Summary

This clinical trial is looking at how a specific type of anesthesia called low-flow sevoflurane affects lung function during and after surgery on the chest, where only one lung is used for breathing (this is called one-lung ventilation). The goal is to see if using low-flow anesthesia, which uses less gas, helps the lungs work better and reduces breathing problems after surgery compared to the usual amount of anesthesia gas.

The study will include adults aged 18 to 75 who are having planned chest surgery, such as minimally invasive procedures or open surgery, and who are generally healthy enough for surgery without severe lung or heart problems. Participants will receive either low-flow or standard anesthesia during their surgery, and the doctors will monitor their lung function and oxygen levels during and after the operation. This research could help improve anesthesia methods to make recovery easier and safer for future patients having similar chest surgeries.

Gender

ALL

Eligibility criteria

• Inclusion Criteria:
• • Age between 18 and 75 years American Society of Anesthesiologists (ASA) physical status I-III Scheduled for elective video-assisted thoracoscopic surgery (VATS) or thoracotomy No acute respiratory failure
• Exclusion Criteria:
• • Severe chronic obstructive pulmonary disease (COPD) or restrictive lung disease Body mass index (BMI) greater than 40 kg/m² Cardiac dysfunction with ejection fraction (EF) less than 40% Requirement for emergency thoracic surgery