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Search / Trial NCT07085611

Neutralizing Power of Serum Antibodies - 2

Launched by CENTRE HOSPITALIER RÉGIONAL D'ORLÉANS · Jul 24, 2025

Trial Information

Current as of August 24, 2025

Not yet recruiting

Keywords

Neutralizing Antibodies Sars Co V 2 Monkeypox Vaccination Serum Mucosal Immunity

ClinConnect Summary

This study is looking at how well antibodies—special proteins in your blood and nose that fight infections—work over time after people get vaccines or treatments for COVID-19 and Monkeypox. Specifically, the researchers want to understand how strong these antibodies are at stopping the virus, which helps protect people from getting sick again. This is especially important for people with weaker immune systems or other health conditions that make infections more dangerous.

Adults who are getting, or plan to get, vaccines or antibody treatments for COVID-19 or Monkeypox may be able to join the study. Participants will need to give their written permission to take part. The study does not include pregnant or breastfeeding women, people under legal protection, or those without social security coverage. If you join, you might have blood and nasal samples taken at different times to measure your antibody levels. The study is not yet open for enrollment but aims to help us better understand how long protection lasts after vaccination or treatment.

Gender

ALL

Eligibility criteria

  • Inclusion Criteria:
  • Adults (≥18 years)
  • Patients receiving or scheduled to receive anti-SARS-CoV-2 and/or anti-MPXV vaccines or monoclonal antibodies
  • Patients have provided written informed consent
  • Exclusion Criteria:
  • Persons under guardianship or curatorship
  • Persons under legal protection,
  • Persons persons deprived of liberty
  • Persons not affiliated to a social security scheme
  • Pregnant or breastfeeding women

About Centre Hospitalier Régional D'orléans

The Centre Hospitalier Régional d'Orléans is a leading healthcare institution dedicated to advancing medical research and improving patient care through innovative clinical trials. Located in Orléans, France, the center is committed to fostering a collaborative environment that integrates clinical expertise with cutting-edge research methodologies. By facilitating multidisciplinary studies across various therapeutic areas, the Centre Hospitalier Régional d'Orléans aims to enhance treatment protocols and contribute to the global body of medical knowledge, ultimately benefiting patients and the healthcare community at large.

Locations

Orléans, , France

Patients applied

0 patients applied

Trial Officials

Thierry PRAZUCK, Dr

Principal Investigator

CHU Orléans

Timeline

First submit

Trial launched

Trial updated

Estimated completion

Not reported