CT-Based Scoring System to Predict Surgical Need in Tracheal Stenosis (TSMAS Study)

Launched by ONDOKUZ MAYIS UNIVERSITY · Jul 18, 2025

Keywords

ClinConnect Summary

This clinical trial is studying a new way to use CT scans—a type of detailed X-ray—to help doctors decide the best treatment for people with tracheal stenosis, which is a narrowing of the windpipe. The researchers want to create a simple scoring system called the Tracheal Stenosis Morphology and Attenuation Score (TSMAS) that looks at specific features on the CT images, like how narrow the airway is and the thickness of the tracheal wall. This score could help predict whether a patient will need surgery or if less invasive treatments, like using a scope to open the airway, might work instead.

People who might be eligible for this study are adults (18 years or older) who have been diagnosed with tracheal stenosis and have had a CT scan of their chest at the time of diagnosis. The CT images need to be clear and saved in a specific digital format so they can be analyzed properly. Patients who have had previous surgery for tracheal stenosis, have certain types of tumors or cancer causing the narrowing, or have received radiation therapy to the neck area will not be able to join. While this study is not yet recruiting participants, those who take part will have their existing CT scans reviewed to help develop this scoring tool, which aims to improve treatment decisions in the future without needing extra tests or procedures.

Gender

ALL

Eligibility criteria

• Inclusion Criteria:
• • Age ≥ 18 years
• • Diagnosed with tracheal stenosis
• • Underwent thoracic CT imaging at the time of diagnosis
• • CT scans available in adequate quality and in DICOM format
• • No prior surgical treatment for tracheal stenosis before CT imaging
• Exclusion Criteria:
• • Tracheal stenosis due to malignancy, foreign body, or tracheobronchial tumors
• • History of tracheal surgery before CT imaging
• • Poor quality CT images (e.g., motion artifacts, incomplete tracheal segments)
• • Patients with a history of radiotherapy (RT) to the neck or mediastinum