Establishment of a Classification System and Postoperative Risk Warning Model for Patients Undergoing Bariatric Metabolic Surgery for Severe Obesity

Launched by THE THIRD XIANGYA HOSPITAL OF CENTRAL SOUTH UNIVERSITY · Jul 29, 2025

Keywords

ClinConnect Summary

This clinical trial is studying how to better understand and predict risks for people undergoing weight-loss surgery, specifically for severe obesity. The researchers want to create a system that can classify patients based on their health details before and after surgery and use this information to warn doctors and patients about possible complications. By looking closely at medical tests and other health data from about 2,000 patients, the study aims to develop a smart digital tool that helps manage care and improve recovery after surgeries like sleeve gastrectomy or gastric bypass.

Adults between 18 and 50 years old who are planning to have bariatric surgery and have had a stable weight recently may be eligible to join. People with certain health problems, such as serious thyroid issues, kidney or liver problems, or those taking certain medications that affect metabolism, would not qualify. Participants will provide health information before and after surgery, which will be used to better understand who might face risks after the procedure. This study hopes to make bariatric surgery safer and more personalized for future patients.

Gender

ALL

Eligibility criteria

• Inclusion Criteria:
• • Patients who meet the clinical indications for bariatric/metabolic surgery;
• • Adults aged 18 to 50 years; ③ Stable body weight (change within ±5% over the past 3 months); ④ Undergoing either laparoscopic sleeve gastrectomy (LSG) or laparoscopic Roux-en-Y gastric bypass (LRYGB).
• Exclusion Criteria:
• • ① Patients with conditions affecting the immune or metabolic systems (e.g., endocrine disorders such as untreated hypothyroidism/hyperthyroidism, cancer);
• • Patients with renal or hepatic impairment;
• • Patients who have taken medications that may affect metabolism within the past 3 months (e.g., weight-loss drugs, asthma medications, psychiatric medications, corticosteroids);
• • Patients who have previously undergone bariatric surgery and are undergoing revisional surgery; ⑤ Patients with psychiatric disorders, especially those with comorbid behavioral or personality disorders (e.g., binge eating disorder);
• • Patients currently participating in other clinical studies that may conflict with this study or those who refuse to sign the informed consent form.