Impact of Nd:YAG Laser Photobiostimulation on Healing of Gingiva
Launched by MEDICAL UNIVERSITY OF SOUTH CAROLINA · Jul 23, 2025
Trial Information
Current as of August 19, 2025
Not yet recruiting
Keywords
ClinConnect Summary
This clinical trial is studying whether using a special low-level laser treatment called Nd:YAG photobiostimulation can help the gums heal faster and better after a tooth is pulled and the area is prepared for future dental work. The researchers want to see if applying this laser treatment a few times in the first week after the tooth extraction can reduce pain, improve healing, and increase patient satisfaction compared to the usual care without the laser.
Adults aged 18 and older who need to have a tooth removed and the surrounding bone preserved may be eligible to participate, as long as they don’t have active gum disease, recent infections, or certain medications that could affect healing. If you join the study, you would receive the standard tooth extraction care, and some participants will also get the laser treatment on days 1, 3, and 7 after the procedure. The team will check healing by measuring wound size, saliva markers, pain levels, and how satisfied you feel with the recovery. This study is not yet recruiting but aims to find better ways to help patients heal more comfortably after dental surgery.
Gender
ALL
Eligibility criteria
- Inclusion Criteria:
- • Participants who are ≥ 18 years old,
- • Patients who are scheduled for the treatment of tooth extraction and alveolar ridge preservation (ARP)
- • No contraindications for tooth extraction and alveolar ridge preservation based on electronic health records.
- • Participants who can express the level of pain
- • Participants who self-report "not pregnant"
- Exclusion Criteria:
- • Untreated periodontal disease
- • Acute infection of the teeth
- • Use of antibiotics within the last three months.
- • Pregnant or lactating women
- • Use of bisphosphonates based on EHR
- • Alveolar bone defects occurred or were detected during tooth extraction
About Medical University Of South Carolina
The Medical University of South Carolina (MUSC) is a leading academic health center dedicated to advancing medical research and improving patient care through innovative clinical trials. With a strong emphasis on translational medicine, MUSC leverages its extensive resources and expertise to facilitate groundbreaking studies across various medical disciplines. The institution is committed to fostering collaboration among researchers, healthcare professionals, and patients, ensuring that cutting-edge discoveries translate into effective treatments. As a pioneer in health education and research, MUSC plays a vital role in shaping the future of medicine and enhancing health outcomes in the community and beyond.
Contacts
Jennifer Cobb
Immunology at National Institute of Allergy and Infectious Diseases (NIAID)
Locations
Charleston, South Carolina, United States
Patients applied
Trial Officials
Pinar Emecen-Huja
Principal Investigator
Medical University of South Carolina
Timeline
First submit
Trial launched
Trial updated
Estimated completion
Not reported