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Search / Trial NCT07095556

Impact of Nd:YAG Laser Photobiostimulation on Healing of Gingiva

Launched by MEDICAL UNIVERSITY OF SOUTH CAROLINA · Jul 23, 2025

Trial Information

Current as of August 19, 2025

Not yet recruiting

Keywords

Inflammation Periodontal Disease Low Level Laser Therapy Gingival Healing Post Operative Pain

ClinConnect Summary

This clinical trial is studying whether using a special low-level laser treatment called Nd:YAG photobiostimulation can help the gums heal faster and better after a tooth is pulled and the area is prepared for future dental work. The researchers want to see if applying this laser treatment a few times in the first week after the tooth extraction can reduce pain, improve healing, and increase patient satisfaction compared to the usual care without the laser.

Adults aged 18 and older who need to have a tooth removed and the surrounding bone preserved may be eligible to participate, as long as they don’t have active gum disease, recent infections, or certain medications that could affect healing. If you join the study, you would receive the standard tooth extraction care, and some participants will also get the laser treatment on days 1, 3, and 7 after the procedure. The team will check healing by measuring wound size, saliva markers, pain levels, and how satisfied you feel with the recovery. This study is not yet recruiting but aims to find better ways to help patients heal more comfortably after dental surgery.

Gender

ALL

Eligibility criteria

  • Inclusion Criteria:
  • Participants who are ≥ 18 years old,
  • Patients who are scheduled for the treatment of tooth extraction and alveolar ridge preservation (ARP)
  • No contraindications for tooth extraction and alveolar ridge preservation based on electronic health records.
  • Participants who can express the level of pain
  • Participants who self-report "not pregnant"
  • Exclusion Criteria:
  • Untreated periodontal disease
  • Acute infection of the teeth
  • Use of antibiotics within the last three months.
  • Pregnant or lactating women
  • Use of bisphosphonates based on EHR
  • Alveolar bone defects occurred or were detected during tooth extraction

About Medical University Of South Carolina

The Medical University of South Carolina (MUSC) is a leading academic health center dedicated to advancing medical research and improving patient care through innovative clinical trials. With a strong emphasis on translational medicine, MUSC leverages its extensive resources and expertise to facilitate groundbreaking studies across various medical disciplines. The institution is committed to fostering collaboration among researchers, healthcare professionals, and patients, ensuring that cutting-edge discoveries translate into effective treatments. As a pioneer in health education and research, MUSC plays a vital role in shaping the future of medicine and enhancing health outcomes in the community and beyond.

Locations

Charleston, South Carolina, United States

Patients applied

0 patients applied

Trial Officials

Pinar Emecen-Huja

Principal Investigator

Medical University of South Carolina

Timeline

First submit

Trial launched

Trial updated

Estimated completion

Not reported