Frequency and Severity of Respiratory Acidosis During One-lung Ventilation, a Retrospective Pilot Study to Compare Clinician Settings and Those Proposed by the VentilO Application

Launched by LAVAL UNIVERSITY · Jul 30, 2025

Keywords

ClinConnect Summary

This clinical trial is looking at how often and how severe a condition called respiratory acidosis happens during one-lung ventilation, a special type of breathing support used during certain chest surgeries. Respiratory acidosis happens when carbon dioxide builds up in the blood because the lungs aren’t removing it properly. The study will compare the usual settings doctors use on the breathing machines with new settings suggested by a smartphone app called VentilO, which aims to better adjust the machine to each patient’s needs.

Adults who are having chest surgery and require one-lung ventilation with a specific breathing method (called volume-controlled ventilation) may be eligible to participate. Participants will have their breathing machine settings studied during surgery to see if the app’s recommendations could improve their care. People without certain important medical data, like blood tests or body measurements, won’t be included. This study is not recruiting yet but aims to help doctors find safer and more personalized ways to support breathing during complex surgeries.

Gender

ALL

Eligibility criteria

• Inclusion Criteria:
• • Adults (≥ 18 years old)
• • Patients intubated and undergoing one-lung ventilation during thoracic surgery
• • Volume-controlled ventilation mode used intraoperatively
• Exclusion Criteria:
• • Arterial blood gas data unavailable during one-lung ventilation
• • Missing demographic data (sex, height, actual weight)