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Search / Trial NCT07103889

Effect of Acute Exercise on Biochemical Parameters in Normal-Weight and Overweight/Obese Adolescent.

Launched by HIGH INSTITUTE OF SPORTS AND PHYSICAL EDUCATION OF KEF · Aug 1, 2025

Trial Information

Current as of August 19, 2025

Not yet recruiting

Keywords

Adolescent Maximal Exercise Blood Biomarkers Liver Enzymes Lipid Profile Renal Function Obesity Overweight Normal Weight

ClinConnect Summary

This clinical trial is studying how a short, intense exercise test called the Spartacus test affects certain blood markers in teenage girls who are either normal weight or overweight/obese. The researchers want to see if this exercise changes how the body processes sugar and fats, how it affects inflammation (which is the body’s response to stress or injury), and whether it causes any changes in liver and muscle health or the balance of important minerals in the blood. Blood samples will be taken before exercise, right after the test, and again 30 minutes later to check these changes.

Girls aged 14 to 18 who are either normal weight or overweight/obese based on their body mass index (BMI) may be eligible to join, as long as they don’t have any chronic illnesses, are not pregnant, and can safely perform intense exercise. Participants will need to give consent along with a parent or guardian. During the study, they will do the exercise test while their health is closely monitored, with blood draws before and after to understand how their bodies respond. This research aims to better understand how exercise impacts health differently in normal-weight and overweight teens, which could help improve future health advice and treatments.

Gender

FEMALE

Eligibility criteria

  • Inclusion Criteria:
  • Female,
  • Aged 14-18 years
  • BMI between the 5th and \<85th percentile for age (normal-weight group), or BMI ≥ 85th percentile for age (overweight/obese group)
  • No chronic illness or contraindication to exercise
  • No regular medication use
  • Written informed consent from participant and parent/legal guardian
  • Exclusion Criteria:
  • Presence of chronic diseases (diabetes, thyroid disorders, etc.)
  • Musculoskeletal or cardiovascular contraindications to maximal exercise
  • Pregnancy
  • Recent infection or inflammation
  • Use of anti-inflammatory or hormonal medications

About High Institute Of Sports And Physical Education Of Kef

The High Institute of Sports and Physical Education of Kef is a leading academic and research institution dedicated to advancing the fields of sports science, physical education, and athletic performance. Committed to fostering excellence in training, education, and scientific inquiry, the institute supports innovative clinical trials and studies aimed at enhancing health, fitness, and sports-related outcomes. Through its multidisciplinary approach, it contributes to the development of evidence-based practices that promote physical well-being and athletic achievement.

Locations

Boulifa, Kef, Tunisia

Patients applied

0 patients applied

Trial Officials

Wissal abassi, Dr

Principal Investigator

Research Unit "Sport Sciences, Health and Movement"(UR22JS01) High Institute of Sport and Physical Education of Kef, University of Jendouba, 7100 Kef, Tunisia.

Timeline

First submit

Trial launched

Trial updated

Estimated completion

Not reported