Establishing Feasibility of Transbronchial Cryoablation With an In-Development Cryoprobe: An Ex-Vivo Human Lung Model

Launched by ENDOCISION TECHNOLOGIES INC. · Aug 4, 2025

Keywords

ClinConnect Summary

This clinical trial is exploring a new way to treat lung cancer using a special tool called a cryoprobe, which works by freezing and destroying cancer cells in the lungs. The study uses human lungs outside the body (from lung transplants) to see if this freezing technique can be safely and effectively applied to lung tumors.

The trial is looking for people who are having lung transplant surgery to help test this method. It is not open to healthy donors or people with lung infections at the time of transplant. Since the study uses lungs removed during transplant surgery, participants won’t undergo extra procedures beyond their planned surgery. This research is still in early stages and aims to find out if this freezing treatment could one day be a safe option for lung cancer patients.

Gender

ALL

Eligibility criteria

• Inclusion Criteria:
• • Patients undergoing lung transplant surgery
• Exclusion Criteria:
• • Organ donors eligible to donate lungs for transplantation Healthy individuals Patients with ongoing pulmonary infection at the time of transplant