Hematological Disorders in EHPVO Patients

Launched by RAHAB NADY · Jul 31, 2025

Keywords

ClinConnect Summary

This clinical trial is studying a condition called extrahepatic portal vein obstruction (EHPVO), where a blood clot blocks a large vein near the liver. This blockage can cause problems like an enlarged spleen, bleeding in the digestive system, and low numbers of blood cells. The study aims to find out if some patients with EHPVO have hidden blood disorders that make clotting more likely. By looking closely at blood tests, researchers hope to identify patterns that could help doctors diagnose and treat these underlying issues earlier, which might prevent complications and improve patient health.

Adults aged 18 and older who have been diagnosed with EHPVO through imaging tests and have good liver function may be eligible to participate. Patients must have complete medical records, including blood counts and clotting test results. Those with liver cirrhosis, certain liver-related high blood pressure, or known blood cancers are not eligible. If you join the study, your existing blood test results will be reviewed to look for signs of hidden blood disorders. This information may help doctors better understand your condition and guide treatment decisions in the future.

Gender

ALL

Eligibility criteria

• Inclusion Criteria:
• • Age 18 years or older . Diagnosis of extra hepatic portal vein obstruction based on imaging ( Doppler, CT , MRI ) preserved liver function . Available complete medical records including CBC , LFTs and coagulation profile .
• Exclusion Criteria:
• • Patients with cirrhosis or intrahepatic portal hypertension • Incomplete or missing medical records • Patients with known hematologic malignancies or undergoing chemotherapy