Comparative Experimental Study Between Bupivacaine and Ropivacaine Regarding Efficacy in Third Molar Removal Surgery Under General Anesthesia

Launched by HENRIQUE TEDESCO · Jul 30, 2025

Keywords

ClinConnect Summary

This clinical trial is studying two different medicines, bupivacaine and ropivacaine, to see which one works better in controlling pain and bleeding during and after wisdom tooth removal surgery performed under general anesthesia (where you are fully asleep). The researchers want to find out if one medicine causes fewer changes in vital signs (like heart rate and blood pressure), helps control bleeding better, or reduces pain more after the surgery.

Adults between 18 and 60 years old who are healthy or have mild health issues and need both lower wisdom teeth removed with similar positions may be eligible to join. If you take part, you will have one surgery where each medicine will be used on different sides of your mouth, and you’ll be asked to rate your pain after the procedure using a simple pain scale. This study is currently looking for volunteers and aims to help doctors choose the safer and more effective medicine for wisdom tooth surgery in the future.

Gender

ALL

Eligibility criteria

• Inclusion Criteria:
• • Patients aged 18 to 60
• • Patients ASA Physical Status Classification I and II
• • Patients with impacted or semi-impacted lower third molars with similar positioning on both sides according to the Pell and Gregory classification
• Exclusion Criteria:
• • Patients who can have surgery under local anesthesia
• • Patients where more procedures are required in the same surgical session