Long-Term Benefits of Eccentric Cycling Exercise in Patients With Type 2 Diabetes Mellitus

Launched by UNIVERSITI SAINS MALAYSIA · Jul 30, 2025

Keywords

ClinConnect Summary

This clinical trial is studying a special type of cycling exercise called eccentric (ECC) cycling to see if it offers long-term benefits for men with type 2 diabetes. Unlike regular cycling, ECC cycling involves muscles working while lengthening, which might affect the body differently. The study will compare how moderate- and high-intensity ECC cycling impacts physical health, exercise ability, and overall quality of life, compared to regular (concentric) cycling. Researchers want to find out if ECC cycling could be a good option or addition to current exercise routines for managing type 2 diabetes.

Men between 30 and 60 years old with type 2 diabetes, who are not regularly active and have controlled blood sugar levels (HbA1C between 6-8%), may be eligible. Participants will start with two short sessions to get used to the cycling, then exercise twice a week for 10 weeks, either doing moderate- or high-intensity ECC cycling or moderate-intensity regular cycling. Before, during, and after the program, their health and fitness will be checked to see how the exercises affect them. People with serious health problems, those using insulin injections, or who have recent exercise experience won’t qualify. This study aims to find safe, effective ways to improve health and daily life for men managing type 2 diabetes.

Gender

MALE

Eligibility criteria

• Inclusion Criteria:
• • Male diagnosed with T2DM
• • Age 30 - 60 years old
• • Height ≥155cm (To ensure proper ergonomics, comfort and safety during cycling)
• • HbA1C level between 6-8%
• • No resistance exercise for ≤ 3 months before participating in the current study.
• • Physical inactivity (moderate to vigorous exercise ≤60 minutes weekly based on International Physical Activity Questionnaires-Short Form (IPAQ-SF))
• Exclusion Criteria:
• • Acute illness or any foot ulcer, diabetic ulcer, retinopathy, kidney, musculoskeletal, cardiovascular, or neurological disorder that could impair exercise performance or pose a risk to participants during exercise.
• • Insulin injection