Cardio-circulatory and Respiratory Monitoring for Prediction of Outcome in Mechanically Ventilated Chronic Obstructive Pulmonary Disease Patients

Launched by ASSIUT UNIVERSITY · Jul 31, 2025

Keywords

ClinConnect Summary

This clinical trial is studying a new way to help doctors decide when patients with Chronic Obstructive Pulmonary Disease (COPD) who are on breathing machines (ventilators) are ready to come off them. COPD is a lung condition that can cause serious breathing problems, sometimes requiring machines to help patients breathe during flare-ups. Taking patients off these machines at the right time is very important because staying on a ventilator too long can lead to complications like infections or muscle weakness. This study will look at a monitoring tool called ICON®, which uses sensors on the skin to measure how well the heart and lungs are working together. Researchers want to see if this tool can better predict when patients are ready to stop using the ventilator compared to the usual tests doctors use now.

People who might be eligible for this study are adults with COPD who have been on a breathing machine for more than 2 days due to a sudden worsening of their condition and who meet certain medical criteria to start the process of coming off the ventilator. Patients with certain complications like lung collapse or fluid around the lungs or heart are not eligible, as well as those with injuries that prevent the use of the monitoring device. Participants can expect to have this non-invasive monitoring device attached to their chest while doctors assess their readiness to breathe on their own. The goal is to find better ways to safely reduce the time patients spend on ventilators, potentially improving recovery and reducing risks.

Gender

ALL

Eligibility criteria

• Inclusion Criteria:
• • All COPD patients who are mechanically ventilated for more than 48 h due to acute exacerbation and fulfilling weaning criteria will be included in the study.
• Exclusion Criteria:
• • 1. Patients younger than 18 years old.
• • 2. Patients with pneumothorax, pleural, or pericardial effusion.
• • 3. Patients with injuries, burns, or wounds which precludes the proper application of the device electrodes.