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Search / Trial NCT07111208

Ambient Air and Noise Effect on Cardiovascular Health Risk and Lifestyle Intervention to Attenuate It (METSGREEN)

Launched by REGINA GRAZULEVICIENE · Jul 31, 2025

Trial Information

Current as of August 22, 2025

Not yet recruiting

Keywords

Ultrafine Particles Noise Pollution Cardiovascular Risk Metabolic Syndrome Physical Activity Mediterranean Diet Environmental Exposure

ClinConnect Summary

This study is looking at how tiny air pollution particles and noise from the environment might affect the risk of heart disease and related health problems in people aged 45 to 64 living in Kaunas City. It also wants to find out if simple lifestyle changes—like daily walks in green areas or following a Mediterranean diet—can help lower these risks and improve health. The study has two parts: one where about 1,000 people fill out an online health and lifestyle survey, and another where 180 people take part in a more detailed clinical trial.

If you join the clinical trial, you will be randomly placed into one of three groups: continuing your usual habits, adding daily walks in nature, or following a Mediterranean diet. You’ll wear a wristband for a week to track your activity, heart rate, and sleep. You’ll also visit the clinic twice—in the beginning and after one week—for some basic health checks like blood pressure and waist size, and to give blood samples. To join, you need to be between 45 and 64 years old, live in Kaunas City, and have some signs of metabolic health issues like high blood pressure or a larger waist size. People with certain heart problems, very high blood pressure, neurological issues, pregnancy, or alcohol dependence cannot join. This study hopes to give useful advice on how to reduce the impact of pollution and noise on heart health through everyday lifestyle changes.

Gender

ALL

Eligibility criteria

  • Inclusion Criteria:
  • Age 45-64 years
  • Residence in Kaunas City
  • Presence of metabolic disorder indicators (e.g., increased waist circumference and/or elevated blood pressure)
  • Willingness to participate and provide written informed consent
  • Agreement to wear a wristband sensor continuously for 7 days
  • Exclusion Criteria:
  • Unstable angina or cardiomyopathy
  • Blood pressure \>160/110 mmHg
  • Neurological diseases or limited mobility
  • Presence of a cardiac pacemaker
  • Pregnancy
  • Alcohol dependence

About Regina Grazuleviciene

Regina Grazuleviciene is a clinical trial sponsor specializing in advancing medical research through the design and management of clinical studies. With a focus on ensuring rigorous methodology and ethical standards, the sponsor contributes to the development of innovative healthcare solutions aimed at improving patient outcomes. Their commitment to scientific excellence supports the progression of evidence-based medicine across various therapeutic areas.

Locations

Kaunas, , Lithuania

Patients applied

0 patients applied

Trial Officials

Regina Grazuleviciene, prof.

Principal Investigator

Vytautas Magnus University

Timeline

First submit

Trial launched

Trial updated

Estimated completion

Not reported