Occurrence of Severe Cardiac Rhythm and Conduction Disturbances in Emergency Department Patients With Non-ST Elevation Acute Coronary Syndrome

Launched by UNIVERSITY HOSPITAL, STRASBOURG, FRANCE · Aug 1, 2025

Keywords

ClinConnect Summary

This clinical trial is studying how often serious heart rhythm problems happen in patients who come to the emergency room with a certain type of heart condition called non-ST elevation acute coronary syndrome (NSTE-ACS). This condition is a type of heart attack or unstable chest pain that doesn’t show a specific pattern on an ECG test. While serious heart rhythm issues are well-known in other types of heart attacks, it’s unclear how often they occur in people with NSTE-ACS. The study aims to find out if these problems are rare enough that not every patient needs continuous heart monitoring in the emergency room.

Adults 18 years and older who are diagnosed with NSTE-ACS in the emergency room and can understand the study information may be eligible to participate. People with certain other heart conditions or serious illnesses won’t be included. If you join the study, doctors will monitor your heart rhythm during your hospital stay and collect information about your care and health outcomes for up to 30 days. This will help doctors better understand risks and improve care for people with this type of heart problem in the future.

Gender

ALL

Eligibility criteria

• Inclusion Criteria:
• • Adult (≥ 18 years old) patient admitted to the emergency department
• • Able to understand the information provided
• • Diagnosis of non-ST segment elevation ACS established according to the lastest guidelines from the European Society of Cardiology and the 4th Universal Definition of myocardial infarction
• • No objection to participation in the study after receiving appropriate information
• Exclusion Criteria:
• • Patients subject to legal protection
• • Patient with cognitive impairment
• • Myocardial injury and/or symptoms attributable to Takotsubo syndrome, myocarditis, pericarditis, or acute heart failure
• • Clinical evidence suggestive of type 2 myocardial infarction, including acute anemia with hemoglobin \< 10 g/dL, sepsis, acute hypoxemic respiratory failure