Pediatric Intravenous Contrast-Enhanced Ultrasound(CEUS) in China

Launched by THE CHILDREN'S HOSPITAL OF ZHEJIANG UNIVERSITY SCHOOL OF MEDICINE · Aug 3, 2025

Keywords

ClinConnect Summary

This clinical trial is studying a special type of ultrasound called intravenous contrast-enhanced ultrasound (CEUS) to see how well it helps diagnose tummy (abdominal) problems in children. These problems include things like lumps or injuries inside the belly, unexplained fluid buildup, or other unclear abdominal issues. The study aims to find out if this ultrasound method is useful, safe, and how doctors can perform it in a consistent way.

Children from 29 days old up to 18 years who have been diagnosed with abdominal lumps, injuries, fluid in the abdomen, or suspected abdominal problems that other tests couldn’t explain may be eligible to join. Participants will have at least one CEUS ultrasound exam, and possibly more depending on the results. They will also have a regular abdominal ultrasound and will be asked to keep a simple diary about their symptoms and treatments for 30 days. This study is currently recruiting patients, and it’s important that participants do not have certain heart, lung, blood, or allergy conditions that could make the test unsafe.

Gender

ALL

Eligibility criteria

• Inclusion Criteria:
• • 1. Age 29 days to 18 years old;
• • 2. The clinical diagnosis was abdominal space-occupying lesions, blunt abdominal trauma, ascites of unknown cause, and children with suspected abdominal disease but other examinations could not identify the cause.
• Exclusion Criteria:
• • 1. Allergic to sulfur hexafluoride or other components;
• • 2. Heart disease with right-to-left shunt/severe pulmonary hypertension /uncontrolled systemic hypertension/respiratory failure/heart failure/severe arrhythmia;
• • 3. Electrocardiogram, echocardiography or clinical manifestations of myocardial ischemia;
• • 4. Patients with severe blood system diseases or infectious diseases;
• • 5. Hypercoagulable state and recent history of thrombosis;
• • 6. Severe hepatic and renal insufficiency;
• • 7. Patients with respiratory tract infection or congenital respiratory malformation.