Sarcopenia and Related Factors in Patients With Multiple Sclerosis

Launched by SELCUK UNIVERSITY · Aug 4, 2025

Keywords

ClinConnect Summary

This clinical trial is studying how common sarcopenia—a condition that causes loss of muscle strength and mass—is in people with Multiple Sclerosis (MS). MS is a disease that affects the nervous system and can lead to problems with movement and muscle weakness. The study aims to understand how sarcopenia relates to symptoms like tiredness, disability level, nutrition, and physical activity in people with MS. Researchers want to learn more about muscle strength, body changes, and how diet and exercise might affect muscle health in this group.

People who are 18 years or older, have a confirmed diagnosis of MS, are currently stable (no recent attacks), and can still walk with some independence may be eligible to join. Participants will be asked to undergo tests that measure muscle strength, physical abilities, and body composition, as well as provide information about their nutrition and activity levels. This study hopes to find ways to detect muscle loss early and improve quality of life for people living with MS. If you meet the eligibility criteria and are interested, this study is currently recruiting participants.

Gender

ALL

Eligibility criteria

• Inclusion Criteria:
• • Being 18 years of age or older,
• • Having been diagnosed with Multiple Sclerosis (confirmed by a neurologist),
• • Being in a stable phase of the disease (having not had an attack in the last 3 months),
• • Having preserved walking ability (EDSS score ≤6.5),
• • Being able to give informed consent to participate in the study.
• Exclusion Criteria:
• • Having another neuromuscular disease.
• • Having developed significant muscle loss within the last 6 months due to use of corticosteroids or immunosuppressive therapy.
• • Having systemic diseases that can cause muscle loss, such as cancer, rheumatic diseases, or severe metabolic disorders.
• • Having undergone major surgery or a history of serious trauma within the last 3 months.
• • Being pregnant or breastfeeding.