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Search / Trial NCT07121543

Biological Drivers of Cervical Cancer and Side Effects From Radiation Therapy

Launched by UNIVERSITY OF CALIFORNIA, SAN DIEGO · Aug 6, 2025

Trial Information

Current as of August 19, 2025

Recruiting

Keywords

Radiotherapy Cervical Cancer Translational Research Biomarkers

ClinConnect Summary

This study is looking at how radiation therapy, a common treatment for cervical cancer, might change certain proteins and molecules in the cancer tissue over time. By understanding these changes, researchers hope to learn more about how cervical cancer behaves and how the treatment affects the body. Women who are already planned to receive radiation therapy as part of their usual care will be asked to give blood samples and small tissue samples from the cervix or nearby areas before treatment starts, during treatment, and on the last day of radiation.

To take part, women need to be 18 years or older, have a confirmed diagnosis of cervical cancer, and be scheduled to receive a specific type of radiation called brachytherapy. Pregnant or breastfeeding women, or those who cannot provide tissue samples, cannot join. Participants can expect to provide these samples during their regular treatment visits, which helps doctors study the effects of radiation without extra procedures. This study is currently looking for volunteers who meet these criteria.

Gender

FEMALE

Eligibility criteria

  • Inclusion Criteria:
  • Age 18 years or older
  • Pathological diagnosis of cervical cancer
  • Scheduled to receive brachytherapy for cervical cancer
  • Exclusion Criteria:
  • Pregnancy or lactation
  • Inability to provide a tissue sample

About University Of California, San Diego

The University of California, San Diego (UCSD) is a leading academic institution renowned for its commitment to advancing healthcare through innovative research and clinical trials. With a robust focus on translational medicine, UCSD leverages its interdisciplinary approach to explore groundbreaking therapies and interventions across a wide range of medical fields. The university's state-of-the-art facilities and collaboration with top-tier faculty and researchers ensure a comprehensive and ethical framework for conducting clinical trials, ultimately aiming to enhance patient outcomes and contribute to the global body of medical knowledge.

Locations

La Jolla, California, United States

Patients applied

0 patients applied

Trial Officials

Jyoti Mayadev, MD

Principal Investigator

University of California, San Diego

Timeline

First submit

Trial launched

Trial updated

Estimated completion

Not reported