Oregano and Basil Leaves and Coronary Artery Disease

Launched by SHAHID BEHESHTI UNIVERSITY OF MEDICAL SCIENCES · Aug 8, 2025

Keywords

ClinConnect Summary

This clinical trial is looking at whether eating more oregano and basil leaves can help people who have recently experienced unstable angina, a condition where the heart doesn’t get enough blood and oxygen. The study will see if these herbs, which contain natural substances called polyphenols, can reduce inflammation and improve cholesterol levels in the blood. Researchers will also measure the amount of these substances in the urine to understand how the body processes them.

To join this study, you must have been diagnosed with unstable angina, but people with certain other heart attacks, serious liver or kidney problems, autoimmune diseases, or those who are pregnant or breastfeeding cannot take part. While the trial is not yet recruiting participants, those who join will be asked to include oregano and basil leaves in their diet, and the researchers will monitor their blood and urine to see if there are any health benefits. This study aims to find simple, natural ways to support heart health after unstable angina.

Gender

ALL

Eligibility criteria

• Inclusion Criteria:
• • Patients diagnosed with unstable angina
• Exclusion Criteria:
• • Patients diagnosed with STEMI
• • Patients undergoing coronary artery bypass grafting
• • Liver cirrhosis and advanced chronic kidney disease (CKD 5)
• • Having known inflammatory and autoimmune diseases, such as inflammatory bowel disease (IBD) and rheumatoid arthritis, or taking glucocorticoid medications
• • Pregnancy or breastfeeding