French AKI Registry (FAKIR): A Multicenter Study on the In-Hospital Management and Outcomes of Severe Acute Kidney Injury in Nephrology Units

Launched by UNIVERSITY HOSPITAL, STRASBOURG, FRANCE · Aug 7, 2025

Keywords

ClinConnect Summary

This clinical trial, called the French AKI Registry (FAKIR), is studying how patients with severe acute kidney injury (AKI) are cared for while in the hospital and what happens to their health afterward. AKI is a sudden loss of kidney function that can be serious, especially in its more advanced stages (called stage 2 or 3). These severe cases can lead to long-term kidney problems, heart issues, and even increase the risk of death. The study aims to understand how doctors in kidney care units manage these patients and how these treatments affect patients’ kidney health and heart health up to one year after their hospital stay.

Adults aged 18 and older who are admitted to a nephrology (kidney) hospital ward with moderate to severe AKI (stage 2 or 3) may be eligible to take part. Participants will be followed during their hospital stay and then checked at 3, 6, and 12 months after leaving the hospital. These follow-ups will look at kidney function, heart health, any hospital readmissions, and survival. The information gathered will help doctors improve care and develop better plans to support patients recovering from severe AKI. This study is not yet recruiting participants.

Gender

ALL

Eligibility criteria

• Inclusion Criteria:
• • Age ≥ 18 years at admission
• • Hospitalized in a nephrology ward (standard or intensive nephrology care unit)
• • Diagnosis of acute kidney injury (AKI) stage 2 or 3 according to KDIGO criteria at the time of admission
• • Availability of follow-up data at 3 months (clinical or laboratory)
• Exclusion Criteria:
• • AKI stage 1 only
• • AKI acquired outside the nephrology department without subsequent transfer to nephrology
• • Hospitalized for another reason without documented AKI stage 2 or 3
• • Refusal or opposition to data reuse for research purposes
• • Under legal protection (guardianship or trusteeship) without a representative to provide non-opposition
• • Incomplete medical records preventing collection of required baseline data