Prognostic Power of the VEXUS Score in Septic Shock: Effectiveness in Mortality Prediction

Launched by ANTALYA TRAINING AND RESEARCH HOSPITAL · Aug 14, 2025

Keywords

ClinConnect Summary

This clinical trial is looking at a tool called the VEXUS Score to see how well it can predict the chances of survival for patients who have septic shock, a serious condition caused by a severe infection leading to low blood pressure and organ problems. The study will take place in intensive care units, where patients with septic shock are closely monitored. Researchers want to find out if the VEXUS Score can help doctors identify which patients are at higher risk of dying, so they can provide better care.

Adults over 18 who are being treated for septic shock in intensive care units may be eligible to join the study, as long as they can safely have an ultrasound exam of their veins. People with certain conditions, like severe obesity that makes ultrasound difficult, chronic kidney disease requiring dialysis, serious heart or liver problems, or blood clots in key veins, would not be able to participate. If you join the study, you can expect to have ultrasound scans to assess your veins, which is a painless procedure using sound waves to create images inside the body. The study is not yet recruiting participants, but if you or a loved one is in intensive care with septic shock, this research could help improve how doctors predict outcomes and tailor treatments in the future.

Gender

ALL

Eligibility criteria

• Inclusion Criteria:
• • Age\>18
• • Patients monitored for septic shock in intensive care unit
• • Signed informed consent
• Exclusion Criteria:
• • Age \<18
• • Severe obesity precluding adequate ultrasonographic imaging.
• • Patients in whom venous structures cannot be clearly assessed via ultrasonography due to anatomical or technical reasons (e.g., adhesions following abdominal surgery).
• • Patients receiving dialysis due to chronic kidney disease or initiating dialysis for acute kidney failure.
• • Chronic heart failure.
• • Patients with advanced valvular insufficiency or advanced pulmonary hypertension.
• • Patients with portal hypertension or advanced-stage liver cirrhosis.
• • Presence of acute or chronic thrombosis in the inferior vena cava or other venous structures within the scoring area.
• • Refusal to participate