Mango Intake and Gut and Cardiometabolic Health in Hispanic/Latino Adolescents

Launched by UNIVERSITY OF CALIFORNIA, DAVIS · Aug 14, 2025

Keywords

ClinConnect Summary

This clinical trial is looking at how eating mangos every day for four weeks might affect the health of Hispanic/Latino teenagers, especially their gut health, metabolism (how the body processes food and energy), blood vessels, and inflammation. Researchers want to see if replacing typical snack foods like cookies, chips, or candy with mangos can lead to better overall health in adolescents who are at higher risk for heart and metabolic problems.

Teens between 12 and 19 years old who identify as Hispanic or Latino and have a body mass index (BMI) in the 85th percentile or higher (which means they are overweight or obese) may be eligible to join. Participants need to be willing to eat mangos daily instead of their usual snacks and use a smartphone or tablet to take photos related to the study. Certain conditions, such as food allergies, current use of prescription medications (except asthma inhalers), or following vegetarian/vegan diets, would exclude someone from participating. If eligible, teens can expect to eat mangos daily for a month and have their health monitored to see how this simple change might benefit them. The study isn’t recruiting yet, but it aims to provide helpful information about healthy eating habits for young people in this community.

Gender

ALL

Eligibility criteria

• Inclusion Criteria:
• • - Male or Female 12-19 years old
• • BMI ≥ 85th percentile (https://www.bcm.edu/bodycomplab/BMIapp/BMI-calculator-kids.html)
• • Self-reported Hispanic/Latino
• • Subject is willing and able to comply with the study protocols
• • Subject is willing to consume the test products
• • Female-specific criteria: if menstruating, eumenorrheic (regular monthly menstrual cycles of 25-30-days in length)
• • Access to a smartphone or tablet at least 1x / day and willing to take pictures associated with the products to be consumed in the study
• Exclusion Criteria:
• • - Reported food allergies.
• • Currently taking prescription drugs, with the exception of asthma inhalers, which are allowed
• • BMI \<85th percentile (https://www.bcm.edu/bodycomplab/BMIapp/BMI-calculator-kids.html)
• • Current participation in a moderate or high-intensity daily exercise routine
• • Self-reported disease, serious illness, or who are currently under acute medical care.
• • Currently taking prescription drugs.
• • Any supplement use, including multi-vitamin/ mineral, herbal, plant or botanical, fish oil, and oil supplements, and not willing to discontinue before starting the study.
• • Vegetarian or vegan diet
• • Self-reported malabsorption or gastrointestinal issues
• • Fruit and vegetable intake exceeding daily recommendations of 5 servings
• • Smoking (vaping, conventional nicotine-containing products or marijuana)
• • Current enrollee in a clinical research study