Immersive Virtual Reality in Cognitive Rehabilitation of Patients With Post-Stroke Cognitive Impairment

Launched by UNIVERSITY OF CHILE · Aug 8, 2025

Keywords

ClinConnect Summary

This clinical trial is exploring whether using immersive virtual reality (VR) can help improve thinking skills in adults who have mild to moderate memory and attention problems after a stroke. Participants will wear a VR headset and play interactive games designed to exercise their memory, focus, and problem-solving abilities. The program includes 10 sessions, each lasting a short time, held two to three times a week over about four weeks. The study will look at how safe and easy to use this VR therapy is for both patients and therapists, and whether it might improve thinking skills and quality of life.

Adults over 18 who have had a stroke within the last three months and show some cognitive difficulties (like trouble with memory or attention) may be eligible to join. However, people who have vision problems that make using the headset difficult, severe speech problems, serious mental health conditions, or major physical disabilities that affect movement won’t be able to participate. If you join, you can expect to take part in these VR sessions during your outpatient therapy, and the team will carefully watch for any side effects or discomfort. This study is a first step to see if VR could be a helpful new tool in stroke recovery.

Gender

ALL

Eligibility criteria

• Inclusion Criteria:
• • Patients over 18 years of age
• • Patients with a cerebrovascular accident of any etiology with less than 3 months of progression
• • Patients with mild to moderate cognitive impairment post-stroke (impairment in at least one cognitive domain)
• • MoCA score of less than 24 points
• • Referred for cognitive rehabilitation at the Occupational Therapy Unit of HCUCH
• Exclusion Criteria:
• • Patients with refractive errors that prevent the use of the headset
• • Patients with any type of aphasia that prevents the administration of the MoCA test
• • Patients with severe psychiatric disorders (presence of psychotic symptoms or derealization)
• • Patients with severe motor impairments (lack of trunk control or global strength of both upper limbs \< M3)