Moderate-Intensity Exercise and Pain Sensitization in Breast Cancer Survivors: A Case-Based Study
Launched by UNIVERSIDAD REY JUAN CARLOS · Aug 13, 2025
Trial Information
Current as of August 20, 2025
Recruiting
Keywords
ClinConnect Summary
This clinical trial is studying whether a supervised exercise program combining moderate-intensity aerobic (like walking or cycling) and strength training can help reduce pain sensitivity in women who have survived breast cancer and continue to experience pain after their treatment. The study also looks at whether this exercise can improve pain levels, how the body senses pain, overall quality of life, and physical ability.
Women who may be eligible for this study are adults who were diagnosed with stage I to III breast cancer, have finished their main cancer treatments (such as surgery, chemotherapy, or radiation) at least six months ago, and still have ongoing pain or unusual sensations in the area around the treated breast or arm. The exercise program will be carefully supervised to ensure safety, and participants will be supported throughout. It’s important to note that women with certain conditions, like cancer returning in the same area, cancer in both breasts, other types of cancer, or health issues that prevent moderate exercise, would not be eligible. The study is currently recruiting participants and aims to see if this kind of exercise is a safe and helpful way to manage pain after breast cancer treatment.
Gender
FEMALE
Eligibility criteria
- Inclusion Criteria:
- • Adult women diagnosed with stage I-III breast cancer
- • Completion of active treatment (surgery, chemotherapy, and/or radiotherapy) at least 6 months prior to enrollment
- • Presence of persistent pain or altered sensation in the upper quadrant of the affected limb related to oncologic treatment
- Exclusion Criteria:
- • Bilateral breast cancer
- • Locoregional recurrence
- • Other malignancies
- • Pre-existing pain not related to cancer treatment
- • Neurological or cognitive disorders
- • Non-Spanish speakers
- • Contraindications to moderate-intensity physical activity
About Universidad Rey Juan Carlos
Universidad Rey Juan Carlos (URJC) is a prominent academic institution located in Madrid, Spain, dedicated to advancing knowledge and research in various fields, including health sciences. With a commitment to innovation and excellence, URJC actively engages in clinical trials aimed at improving patient care and outcomes. The university's multidisciplinary approach fosters collaboration among researchers, clinicians, and industry partners, ensuring that its clinical research is grounded in scientific rigor and ethical standards. Through its robust infrastructure and expertise, Universidad Rey Juan Carlos is poised to contribute significantly to the advancement of medical research and the development of novel therapeutic interventions.
Contacts
Jennifer Cobb
Immunology at National Institute of Allergy and Infectious Diseases (NIAID)
Locations
Madrid, , Spain
Patients applied
Timeline
First submit
Trial launched
Trial updated
Estimated completion
Not reported