Ultrasonic Versus Conventional Clipping Hemostasis in Laparoscopic Colorectal Surgery

Launched by YONSEI UNIVERSITY · Aug 11, 2025

Keywords

ClinConnect Summary

This clinical trial is studying two different ways to control bleeding during minimally invasive surgery for colon cancer. One method uses an ultrasonic scalpel that seals blood vessels without clips for most vessels, while the other uses traditional metal clips to stop bleeding. The goal is to see which method is safer and more effective by looking at things like bleeding during and after surgery, the amount of fluid drained, and how long patients stay in the hospital.

Adults aged 19 to 80 with confirmed colon cancer who are generally healthy enough for surgery may be eligible to join. Participants will have laparoscopic surgery performed by experienced surgeons, and their care after surgery will be the same regardless of which method is used. The ultrasonic scalpel may reduce some risks linked to clips, such as infections or blockages, but clips will still be used for larger blood vessels if needed. If you join, you’ll be randomly assigned to one of the two methods, and the medical team won’t know which method you receive until after the surgery is done. This helps ensure the study is fair and reliable.

Gender

ALL

Eligibility criteria

• Inclusion Criteria:
• • Adults 19 to 80 years of age
• • Patients with histologically confirmed pathologic adenocarcinoma of the colon
• • Patients with an ECOG score between 0 and 2
• • Patients with a preoperative ASA score of I to III
• • Patients without a history of surgery for abdominal malignancies
• • Patients with no history of anticoagulation prior to surgery
• • Patients who understand the study process and treatment plan and are able to complete the informed consent form themselves
• Exclusion Criteria:
• • Patients with an ASA score of 4 or higher
• • People with blood clotting disorders such as liver cirrhosis, end-stage renal failure, or hematologic disorders
• • Pregnant women
• • Mentally ill patients who have difficulty giving informed consent
• • Preoperative blood hemoglobin (Hb) less than 7 g/dL
• • Patients taking anticoagulants before or after surgery
• • Patients who have undergone emergency surgery
• • Patients who are unable to be followed up on an outpatient basi
• • No Informed consent