a Comparison of the Outcomes Following Intra-articular Dextrose 5% Injection Versus Arthrocentesis in Patients With Anterior Disc Displacement With Reduction of the Tomporomandibular Joint

Launched by CAIRO UNIVERSITY · Aug 15, 2025

Keywords

ClinConnect Summary

This clinical trial is studying two treatments for a jaw joint problem called anterior disc displacement with reduction, which can cause pain, limited ability to open the mouth, and clicking sounds in the joint. The study will compare the effectiveness of injecting a low concentration sugar solution (5% dextrose) directly into the joint versus a procedure called arthrocentesis, which involves flushing the joint to relieve symptoms. Both treatments are being tested in patients who have already tried physical therapy for at least three months but still have pain and trouble moving their jaw.

People who might be eligible for this study are adults between 18 and 50 years old who have this specific jaw joint condition and haven't improved with conservative treatments like physiotherapy. Participants should not have other joint diseases, fractures, neurological problems, or be pregnant or breastfeeding. If chosen, participants can expect to receive one of the two treatments to see which works better in reducing pain and improving jaw movement. This study aims to find out which treatment provides more relief and satisfaction for patients with this jaw condition.

Gender

ALL

Eligibility criteria

• Inclusion Criteria:
• • Inclusion Criteria
• • -Patients diagnosed with anterior disc displacement with reduction of TMJ with pain,limited mouth opening and
• • painful clicking who underwent conservative therapy with physiotherapy but failed to receive any relief after 3
• • months of conservative therapy.
• • Age ranges from 18 to 50 years.
• • Patients with adequate follow up duration for outcome assessment.
• Exclusion Criteria:
• • Patients having pain or reduced mouth opening due to fracture of the condyle.
• • patients having any degenerative changes in the TMJ.
• • patients having other systemic diseases such as polyarthritis.
• • patients having any neurological disorders.
• • Pregnant and lactating women.