Endotracheal Suctionning During Positive Pressure Extubation in ICU

Launched by CENTRE HOSPITALIER RÉGIONAL D'ORLÉANS · Aug 12, 2025

Keywords

ClinConnect Summary

This clinical trial is studying a new way to help patients breathe better after they have had a breathing tube removed in the intensive care unit (ICU). When patients have been on a machine to help them breathe, they often have a tube placed in their windpipe. Removing this tube is called extubation. The trial is looking at whether gently suctioning the windpipe (removing mucus and secretions) during the process of removing the tube, while pressure is still helping the patient breathe, improves oxygen levels in the first few hours afterwards compared to not doing the suctioning.

Adults who have had a breathing tube for more than two days and are ready to have it removed by their doctor may be eligible to take part. People who have certain medical or legal restrictions, or who are pregnant or breastfeeding, cannot join. If you participate, the nursing team will remove the breathing tube using the method being studied, and then will monitor your breathing rate and oxygen levels for three hours afterward to see how well you are doing. This study has not started recruiting patients yet, but if you or a loved one are in the ICU and preparing to come off a breathing machine, this research might be an option to consider in the future.

Gender

ALL

Eligibility criteria

• Inclusion Criteria:
• • Adult patient
• • Intubated for more than 48 hours
• • Patient for whom extubation is prescribed by the patient's physician
• Exclusion Criteria:
• • Headboard restriction\>30°.
• • Decision to limit active treatment in advance of reintubation
• • Protected person (under guardianship or curatorship)
• • Person under court protection
• • Persons deprived of liberty
• • Persons not affiliated to a social security scheme
• • Pregnant or breast-feeding woman
• • No co-inclusion with a study whose period of interest is follow-up within 3 hours of extubation.