Real-World Cohort Study of Cardiopulmonary Function in Chinese Patients With Cardiovascular Disease: CPET Evaluation and Five-Year Prognostic Follow-Up Based on a Multicenter Structured Data Platform

Launched by GUANGDONG PROVINCIAL PEOPLE'S HOSPITAL · Aug 18, 2025

Keywords

ClinConnect Summary

This study is looking at how well the heart and lungs work together during exercise in people with different heart conditions. Researchers will use a special test called cardiopulmonary exercise testing (CPET) to measure these functions. The goal is to see if these test results can help predict serious heart-related problems, like heart attacks, strokes, or hospital visits, over the next five years. This information could help doctors better understand which patients are at higher risk and improve their care.

Adults aged 18 to 80 with heart conditions may be eligible to join, as long as they can give informed consent and don’t have other serious health problems that might make exercise unsafe, such as recent heart attacks or severe lung issues. Participants will undergo the exercise test, which is generally safe and involves walking or cycling while their heart and breathing are monitored. The study is not currently enrolling patients but aims to include a wide range of people to gather real-world information from multiple centers. This research could provide valuable insights to help manage heart disease more effectively in the future.

Gender

ALL

Eligibility criteria

• Inclusion Criteria:
• • 1. Age: 18-80 years,
• • 2. Ability to comprehend and provide written informed consent.
• Exclusion Criteria:
• • 1. Comorbid severe conditions (e.g., recent acute myocardial infarction, unstable angina, uncontrolled arrhythmias, severe aortic coarctation or descending aortic aneurysm, acute myocarditis or pericarditis, acute congestive heart failure, acute respiratory failure, resting oxygen saturation \<93%, recent arterial or pulmonary embolism, pulmonary edema).
• • 2. Conditions potentially exacerbated by exercise (e.g., acute cardiac insufficiency, exercise-induced asthma, epilepsy).
• • 3. Physical disability due to musculoskeletal or neuromuscular disorders.
• • 4. Pregnancy or lactation.
• • 5. Patients deemed unsuitable for participation by the investigator.