Real Life Evaluation of the LibAirty Airway Clearance System in Adults With Bronchiectasis (RELACS)

Launched by SYNCHRONY-MEDICAL, LTD · Aug 14, 2025

Keywords

ClinConnect Summary

This clinical trial is looking at how well the LibAirty™ airway clearance system works for adults with bronchiectasis, a lung condition that causes ongoing cough and mucus buildup. The study wants to find out if using this device at home can help reduce flare-ups, called pulmonary exacerbations, and improve symptoms over a year. Participants will keep using their usual treatments and visit their doctors as normal, while occasionally answering short questions about their health and experience with the device.

Adults 21 years or older who have bronchiectasis confirmed by a chest scan and either have a daily productive cough or have recently had two or more flare-ups that needed antibiotics may be eligible. To join, they need to already be prescribed the LibAirty system for home use and have a stable treatment plan. During the 12-month study, participants will use the device as directed and attend up to four clinic visits where health information will be reviewed. The study is not providing the device; participants must have their own prescription and device before joining. This study aims to better understand how this home treatment might help people manage bronchiectasis in real life.

Gender

ALL

Eligibility criteria

• Inclusion Criteria:
• • 1. Have a radiological diagnosis of Bronchiectasis based on high resolution chest CT scan
• 2. Have bronchiectasis characterized by either:
• • Daily productive cough (as determined by a treating physician)
• • OR Available documentation from the last 12 months of 2 or more pulmonary exacerbations requiring antibiotic therapy
• • 3. Be at age ≥ 21 years
• • 4. Prescribed and receives the LibAirty system for home use
• • 5. Be on a standard of care treatment plan that includes at least one physician encounter every 6 months
• • 6. No change in treatment for Bronchiectasis in the 2-month period prior to enrollment
• • 7. Signed informed consent
• Exclusion Criteria:
• • 1. Inability to independently perform therapy with the LibAirty system as directed
• • 2. Any other condition that, in the opinion of the PI, could jeopardize the safety of the subject or impact the validity of the study results.
• • 3. Pregnancy or planned pregnancy during the expected duration of the trial (12 months).