Tacrolimus Eye Drops in Treatment of Vernal Keratoconjunctivitis
Launched by SOHAG UNIVERSITY · Aug 22, 2025
Trial Information
Current as of November 07, 2025
Not yet recruiting
Keywords
ClinConnect Summary
This clinical trial is studying how well Tacrolimus eye drops work and how safe they are for treating vernal keratoconjunctivitis (VKC), which is a type of allergic eye condition causing redness, itching, and discomfort, mostly in children. The study will compare different strengths of Tacrolimus eye drops to the usual treatment with steroid eye drops to see which is better or safer.
Children aged 5 to 15 years old who have moderate to severe VKC may be eligible to take part. However, kids with eye infections, recent eye surgery or injury, certain other eye problems, or those using contact lenses or specific immune-suppressing medicines won’t be able to join. Participants will receive eye drops and be carefully monitored to check how their eyes respond and to watch for any side effects. This study hasn’t started recruiting yet, but it aims to find a safer and effective treatment option for children suffering from this allergic eye condition.
Gender
ALL
Eligibility criteria
- Inclusion Criteria:
- • Patients with moderate to severe active VKC aged between (5-15) years old (pediatric age group)
- Exclusion Criteria:
- • 1. Coexisting eye infections
- • 2. Contact lens use
- • 3. Systemic immunosuppressive drug use
- • 4. Herpes keratitis
- • 5. Recent ocular surgery or trauma
- • 6. Known hypersensitivity to Tacrolimus
- • 7. Ophthalmological comorbidities as cataract, glaucoma, and congenital eye anomalies
- • 8. Impaired renal or hepatic functions
About Sohag University
Sohag University is a distinguished academic institution located in Sohag, Egypt, committed to advancing healthcare through rigorous clinical research. As a clinical trial sponsor, the university leverages its robust infrastructure and multidisciplinary expertise to facilitate innovative studies aimed at improving patient outcomes and contributing to the global body of medical knowledge. With a focus on ethical standards and scientific integrity, Sohag University collaborates with healthcare professionals and researchers to conduct trials that address critical health issues, ensuring the advancement of evidence-based practices in the healthcare community.
Contacts
Jennifer Cobb
Immunology at National Institute of Allergy and Infectious Diseases (NIAID)
Locations
Patients applied
Timeline
First submit
Trial launched
Trial updated
Estimated completion
Not reported