Tislelizumab Combined With Chemotherapy for Different Cycles of Neoadjuvant Therapy for Locally Advanced Resectable Squamous Cell Carcinoma of the Head and Neck (NeoTempo)
Launched by TIANJIN MEDICAL UNIVERSITY CANCER INSTITUTE AND HOSPITAL ยท
Trial Information
Current as of September 12, 2025
Not yet recruiting
Keywords
ClinConnect Summary
This clinical trial is studying a new treatment approach for people with a type of head and neck cancer called squamous cell carcinoma that can be removed by surgery. The study is testing whether giving a medicine called tislelizumab, which helps the immune system fight cancer, combined with chemotherapy before surgery is better when given for either 2 or 4 treatment cycles. The goal is to find out which option works best and is safest for patients.
People who might be eligible for this trial are adults aged 65 to 74 who have this specific type of head and neck cancer that can be surgically removed. If you join the study, you would receive tislelizumab along with chemotherapy for either 2 or 4 cycles before your surgery, and doctors will monitor how well the treatment works and how you respond to it. This study is not yet open for participants, but it aims to help doctors decide the best way to use immunotherapy with chemotherapy before surgery in the future.
Gender
ALL
Eligibility criteria
About Tianjin Medical University Cancer Institute And Hospital
Tianjin Medical University Cancer Institute and Hospital is a leading research and treatment facility dedicated to advancing cancer care and clinical research. Affiliated with Tianjin Medical University, the institute is at the forefront of oncology, combining innovative research methodologies with comprehensive patient care. It emphasizes multidisciplinary approaches to cancer treatment and actively participates in clinical trials aimed at improving therapeutic outcomes. With a commitment to education and collaboration, the institute plays a vital role in enhancing cancer research and treatment protocols both nationally and internationally.
Contacts
Jennifer Cobb
Immunology at National Institute of Allergy and Infectious Diseases (NIAID)
Locations
Patients applied
Timeline
First submit
Trial launched
Trial updated
Estimated completion
Not reported