Cannabidiol as an Adjunct Treatment for Alcohol Withdrawal and Craving

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ClinConnect Summary

This clinical trial is studying whether cannabidiol (CBD), a natural compound found in marijuana, can help reduce symptoms people experience when they stop drinking alcohol, such as anxiety, sleep problems, and cravings. The goal is to see if adding CBD to usual care can make the withdrawal process easier and help people with moderate to severe alcohol use disorder (AUD) feel better during the first few days of quitting alcohol.

Adults who have moderate to severe AUD and are ready to stop drinking may be eligible to join this study. Participants will stay at Johns Hopkins Hospital for about five days and four nights, during which they will stop drinking alcohol and receive usual medical care to manage withdrawal symptoms. Some will receive CBD, while others will get a placebo (a pill with no active ingredient), so researchers can compare the effects. During their stay, participants will be asked about their withdrawal symptoms and sleep quality, and they will provide breath and blood samples to help the study team understand how well CBD works. The trial is not yet recruiting participants, but it will include adults of all genders.

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ALL

Eligibility criteria