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Search / Trial NCT07152067

Stereotactic Focal Radiotherapy as an Alternative Treatment to Active Surveillance for Low and Intermediate Risk Prostate Cancer

Launched by CENTRE HOSPITALIER UNIVERSITAIRE DE LIEGE ·

Trial Information

Current as of November 10, 2025

Not yet recruiting

Keywords

Radiosurgery Focal Treatment Early Prostate Cancer Active Surveillance Phase Ii Randomized Study Stereotactic Radiotherapy Sbrt Quality Of Life

ClinConnect Summary

This clinical trial is looking at a new way to treat certain early-stage prostate cancers using a special type of targeted radiation called stereotactic focal radiotherapy. Instead of watching the cancer closely without treatment (called active surveillance), this approach aims to treat just the visible tumor area with precise radiation. The goal is to see if this focused treatment can lower the chance that patients will need more aggressive treatments later, while also reducing side effects and anxiety that can come from simply waiting and watching.

Men who might be eligible for this study have early-stage prostate cancer with a low to intermediate risk score (CAPRA score of 5 or less), no serious urinary problems, and are otherwise good candidates for active surveillance. The trial will compare two groups: one receiving this focused radiation treatment and the other continuing with active surveillance. If you join, you won’t need anesthesia for the radiation, and the doctors will monitor you closely to see which approach works better at avoiding additional treatments. This study is not yet open for enrollment but is designed to help find safer, less invasive options for men with certain prostate cancers.

Gender

MALE

Eligibility criteria

About Centre Hospitalier Universitaire De Liege

The Centre Hospitalier Universitaire de Liège (CHU Liège) is a leading academic medical center in Belgium, renowned for its commitment to advancing healthcare through innovative clinical research and comprehensive patient care. As a prominent sponsor of clinical trials, CHU Liège integrates cutting-edge scientific inquiry with clinical practice, fostering an environment that enhances the development of new therapies and medical interventions. With a multidisciplinary team of experienced researchers and healthcare professionals, the institution is dedicated to improving patient outcomes and contributing to the global body of medical knowledge. CHU Liège emphasizes collaboration with industry partners and academic institutions to drive excellence in clinical research and support the translation of findings into real-world applications.

Locations

Patients applied

0 patients applied

Trial Officials

Philippe Nickers, MD, PhD

Principal Investigator

University Hospital Liège, Belgium

Mareva Lamande, MD

Principal Investigator

University Hospital Liège, Belgium

Timeline

First submit

Trial launched

Trial updated

Estimated completion

Not reported