Cardiac Amyloid Deposits and Heart Dysfunction in Alzheimer's Disease

Launched by UNIVERSITY HOSPITAL, ESSEN ·

Keywords

ClinConnect Summary

This clinical trial is studying the connection between heart problems and Alzheimer’s disease, focusing on a substance called amyloid that can build up in both the brain and the heart. The researchers want to see if the same type of amyloid deposits that affect memory and thinking in Alzheimer’s disease might also cause issues in the heart. To do this, they will use a special type of scan called a PET scan, which can detect amyloid deposits. Participants will have these scans done not only on their brain but also on their heart, along with an ultrasound of the heart (called an echocardiogram) and a simple check-up to assess memory and thinking skills.

People between the ages of 65 and 74 who are being evaluated for Alzheimer’s disease or mild memory problems may be eligible to join this study. The goal is to better understand how amyloid affects both the brain and heart, which could help doctors improve diagnosis and treatment for both heart-related amyloid disease and Alzheimer’s. If you join, you can expect to have a few scans and exams that are non-invasive and generally safe, helping researchers learn more about these conditions.

Gender

ALL

Eligibility criteria