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Search / Trial NCT07154511

Phase 2 Trial of Tributyrin in People With Parkinson's Disease and Cognitive Impairments

Launched by PRABESH KANEL ·

Trial Information

Current as of September 29, 2025

Recruiting

Keywords

Short Chain Fatty Acid Butyrate Tributyrin Functional Neuroimaging

ClinConnect Summary

This clinical trial is studying whether a supplement called tributyrin can help improve memory, thinking, walking, and balance in adults who have Parkinson’s disease or Parkinson’s disease dementia. Researchers want to find out if taking tributyrin is safe and if it helps with these symptoms compared to a placebo, which is a harmless pill that doesn’t contain the active supplement.

People who join the study will take tributyrin three times a day for about 3 months. Before and after this period, they will come to the clinic for tests that check their thinking and movement abilities, as well as have brain scans to see if there are any changes. This trial is open to adults with Parkinson’s disease or related memory problems. If you or a loved one fits this description and are interested, this study might offer a chance to try a new treatment while helping researchers learn more about managing Parkinson’s symptoms.

Gender

ALL

Eligibility criteria

About Prabesh Kanel

Prabesh Kanel is a clinical trial sponsor dedicated to advancing medical research through the support and oversight of innovative clinical studies. Committed to upholding the highest standards of scientific integrity and patient safety, Prabesh Kanel collaborates with research institutions and healthcare professionals to facilitate the development of novel therapies and improve health outcomes.

Locations

Patients applied

0 patients applied

Trial Officials

Prabesh Kanel, PhD

Principal Investigator

University of Michigan

Timeline

First submit

Trial launched

Trial updated

Estimated completion

Not reported