GLP-1R Actions on Muscle and the Skeleton

Launched by PENNINGTON BIOMEDICAL RESEARCH CENTER ·

Keywords

ClinConnect Summary

This clinical trial, called the GRAMS study, is looking at how a type of medicine called GLP-1 therapy affects muscles and bones after people lose weight. The study wants to understand if this treatment, combined with diet and exercise, can help improve muscle and bone health better than just diet and exercise alone. This is important because weight loss can sometimes affect muscles and bones, especially in people who are overweight or have conditions like osteoporosis (weak bones) or sarcopenic obesity (a mix of muscle loss and obesity).

The study is open to adults aged 18 to 74 years old, regardless of gender. Participants will be asked to follow a diet and exercise plan, and some will receive the GLP-1 therapy while others will not, to see the differences between the groups. The trial is not yet recruiting, but if you qualify, you can expect to be part of a program that helps monitor your muscle and bone health during weight loss. This study could provide helpful information on the best ways to lose weight while keeping your muscles and bones strong.

Gender

ALL

Eligibility criteria