Case Study: Equitable Recruitment for Healthy-Volunteer Oncology Trials
By Robert Maxwell

The first time Maya heard about an early oncology study that needed healthy volunteers she assumed it wasn't for people like her. Outreach felt clinical, flyers went up in the hospital lobby, and the consent paperwork was dense and only in English. What changed was a neighborhood meeting where researchers listened, then redesigned the approach around trust. That pivot became a lesson in equitable recruitment for healthy volunteer oncology trials.
Why equity matters
Recruitment that ignores community context widens health gaps. In a recent ClinConnect survey of 132 clinical professionals, including 78 clinical research coordinators, 68% said lack of community trust was the biggest barrier to diverse healthy-volunteer enrollment, and 54% flagged language access as a critical obstacle. Those numbers echo what we hear from community partners: people join research when they feel respected and informed.A practical turnaround: case study
At a midsize cancer center, a pilot initiative aimed at equitable recruitment for healthy volunteer oncology started by borrowing tactics from other fields. Team leads studied Community-led breast cancer trial outreach models and adapted the approach to early-phase oncology recruitment. They paired peer navigators, inspired by Peer navigator programs for stroke enrollment, with concise, translated materials. Within six months, enrollment of underrepresented volunteers rose from 12% to 38% in that cohort, and appointment no-shows dropped by nearly half.- Recruitment redesign included neighborhood information sessions and mobile enrollment days
- Clinical research coordinators received cultural competency training and small stipends for community time
- Multilingual consent tools for flu vaccine studies served as a template for consent videos and one-page summaries in five languages
Insider perspective: a lead coordinator reflected, em 'Once we started meeting people where they actually live, trust followed. The enrollment conversations became real, not transactional.'
Industry voices and data
Surveyed investigators noted that modern clinical trial platforms help streamline the search process for both patients and researchers, but technology alone is not enough. 74% of respondents said platforms improve discovery, while 61% emphasized the need for human-centered outreach to convert interest into participation. Clinical research coordinators repeatedly pointed to small investments—transport vouchers, flexible hours, translated consent—as high yield. Patient rights and responsibilities- Rights: clear information about risks and benefits, the right to withdraw at any time, privacy protections, and fair compensation when appropriate
- Responsibilities: ask questions, attend scheduled visits when possible, share accurate medical history, and tell the study team about side effects
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